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By Michael A. Palladino
Benjamin Cummings
Paperback (48 pages)
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Completion of the Human Genome Project is just the tip of the iceberg in our understanding of human genetics. How can information gathered during the Human Genome Project be used? This brief booklet explains in accessible language what readers need to understand about the Human Genome Project, including the background, findings, and social and ethical implications. The author, Michael Palladino, also includes relevant Web resources and exercises for readers. |
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By Victor K. McElheny
Basic Books
Hardcover (336 pages)
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Drawing the Map of Life is the dramatic story of the Human Genome Project from its origins, through the race to order the 3 billion subunits of DNA, to the surprises emerging as scientists seek to exploit the molecule of heredity. It’s the first account to deal in depth with the intellectual roots of the project, the motivations that drove it, and the hype that often masked genuine triumphs. Distinguished science journalist Victor McElheny offers vivid, insightful profiles of key people, such as David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny also shows that the Human Genome Project is a striking example of how new techniques (such as restriction enzymes and sequencing methods) often arrive first, shaping the questions scientists then ask. Drawing on years of original interviews and reporting in the inner circles of biological science, Drawing the Map of Life is the definitive, up-to-date story of today’s greatest scientific quest. No one who wishes to understand genome mapping and how it is transforming our lives can afford to miss this book. |
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By Kevin A. Boon
Enslow Publishers
Library Binding (128 pages; 1)
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By Sir Walter Bodmer
Oxford University Press, USA
Paperback (272 pages)
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James Watson, a discoverer of the structure of DNA, described it as "the most golden of molecules," the true chemical for life. Indeed, it is the essential component from which our genes are made. In it is encoded the genetic language that controls our destinies. Astonishingly powerful, just six millionths of a gram of DNA carries as much information as ten volumes of the Oxford English Dictionary. The "Book of Man," is the term used by Walter Bodmer and Robin McKie for the DNA that is the instruction set according to which all humans are made. At conception, a single cell--the fertilized egg--is produced, and it is this one cell that has the potential to form a new and unique individual under the guidance of the DNA within its nucleus. The human body is made up of a hundred million million cells of many different sorts, and all contain the inherited information that comes from that first, single cell created at fertilization. Bodmer and McKie assert that when we learn how to read DNA's pages and chapters we will obtain the information relevant to the understanding of most diseases, individual differences in behavior, and a new awareness of our own history and evolution. The Book of Man explores how genetic information is now being read and interpreted by focusing on biology's most ambitious undertaking to date--the Human Genome Project, an attempt to uncover all the 100,000 genes that control our development and detail the DNA alphabet of each. The authors go on to wrestle with the moral and ethical issues of modern genetics, making a case for a rational appraisal of genetic engineering and for the public to become sufficiently "DNA literate" in order to appreciate the crucial role it plays in our lives. From Gregor Mendel's discovery of the laws of inheritance to the high-tech, crime-stopping power of forensics science and the fascinating but sometimes troublesome implications of the latest science of genetic engineering, The Book of Man brilliantly explores and explains the quest that is changing our understanding of what it means to be a human being. |
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Dartmouth
Hardcover (200 pages)
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- Notes: Brand New from Publisher. No Remainder Mark.
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Begun formally in 1990, the U.S. Human Genome Project's (HGP) goals were to identify all the 20,000 to 25,000 genes in human DNA, determine the sequences of the three billion chemical base pairs that make up human DNA, store this information in databases, improve tools for data analysis, and transfer related technologies to the private sector. It was the first large scientific undertaking to address potential issues that arose from project data, and opened up vast possibilities for the use of genetic data and the alteration of our genetic makeup. This volume is the first to address the diverse range of ethical issues arising from the HGP, and enables professors to bring this critically important topic to life in the classroom.
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ABC-CLIO
Hardcover (566 pages)
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The cavemen did it. The ancient Mayans did it. The folks at Cal Tech, the Sorbonne, and Beijing University are still doing it. Science. Want the whole story? Here it is. The Chronology of Science offers the entire fascinating drama of exploration, discovery, invention, experimentation, hypothesis, and proof. How did the ancient Celts use Stonehenge to map the skies? When did the Arabs come up with the concept of zero? Who first observed the destructive power of germs? Where did the Internet come from? This handy, one-volume reference offers the reader multiple ways to access the thousands of years of science history: chronologies divided into subject areas, including astronomy, biology, chemistry, ecology, mathematics, and physics; 16 feature essays on critical scientific discoveries; hundreds of biographies of key scientists from every age and continent; an extensive glossary of scientific terms; lists of the winners of major scientific prizes; a list of the most up-to-date science websites; and a lengthy bibliography. |
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By National Human Genome Research Institute
National Human Genome Research Institute
CD-ROM
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Understanding the Human Genome Project is a multimedia, educational CD that covers the basics of molecular biology and includes learning modules to help high school students understand genetics, molecular biology and The Human Genome Project. |
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By Rodney Loeppky
Routledge
Hardcover (256 pages)
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This book deals with the rapid changes in contemporary molecular biology, particularly genome sciences, and the manner in which they can be understood through the lens of political economy. Specifically, the work investigates the case of the United States-led Human Genome Project (HGP), in order to show that even large-scale basic science is closely bound up in the progression of capitalist social relations. The work has, in part, been motivated by the lack of rigorous analysis of the HGP. Most of the existing literature tends to present either a chronological review of events surrounding the HGP or describe it thematically. In contrast, this book contributes to a needed discussion concerning the ‘why and how’ of the HGP’s emergence. It elucidates the features within capitalist social relations which have simultaneously enabled the HGP and ensured its amenability to systemic demands. The work’s most compelling elements are both historical and analytical. Historically, it places the HGP within the context of wider political, economic and social issues. Related to this, it puts forward an analytical, explanatory understanding of the project’s emergence, making it a valuable tool for both political economists, science & society theorists, and even bioethicists. |
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University of Notre Dame Press
Paperback (535 pages)
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This work considers the complex, far reaching issues surrounding the Human Genome Project - an international scientific enterprise aimed at attaining a complete sequence and locator map of the human genetic structure by the year 2005 - offering the elimination of genetic abnormalities and diseases. |
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By Joel L. Davis
Wiley
Hardcover (294 pages)
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A giant step for medicine or the most serious threat to personal freedom yet? A cure for cancer or an invitation to genetic discrimination and the search for a master race? Here, not a minute too soon, is a behind-the-scenes account of the Human Genome Project, the most ethically and politically complex scientific undertaking of this generation. Dubbed the ``Holy Grail of Biology,'' the Genome Project will occupy over the next five to 15 years a majority of the best public and private labs and cost more than the GNP of many nations. This book separates fact from fiction, identifies the real moral issues in the debate, and captures the drama--as well as the intrigue and infighting--that has riveted the scientific establishment throughout. |
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